Liu S, D’Amico D, Shankland E, et al. Effect of Urolithin A Supplementation on Muscle Endurance and Mitochondrial Health in Older Adults: A Randomized Clinical Trial. JAMA Netw Open.
Singh A, D'Amico D, Andreux PA, Fouassier AM, Blanco-Bose W, Evans M, Aebischer P, Auwerx J, Rinsch C. Urolithin A improves muscle strength, exercise performance, and biomarkers of mitochondrial health in a randomized trial in middle-aged adults. Cell Rep Med.
Liu S, D’Amico D, Shankland E, et al. Effect of Urolithin A Supplementation on Muscle Endurance and Mitochondrial Health in Older Adults: A Randomized Clinical Trial. JAMA Netw
Clinically proven benefits
Renewal
We conducted a randomized placebo-controlled clinical trial with adults aged 40-65 years old. After 4 months, participants who received a daily 500 mg dose of Mitopure (Urolithin A) had an increase in mitophagy of +40.1%.
Methodology
- Participants90 healthy, overweight, middle aged subjects aged 40 to 65 years
- ProtocolRandomized, double-blind, placebo-controlled — the “gold standard” in studies
- ObjectiveInvestigate the efficacy of Mitopure on mitophagy in otherwise healthy middle-aged, overweight and inactive individuals
Strength
We conducted a randomized placebo-controlled clinical trial with adults aged 40-65 years old. After 4 months, participants who received a daily 500 mg dose of Mitopure (Urolithin A) had a significant improvement in muscle strength, compared with participants in the placebo group.
Methodology
- Participants90 healthy, overweight, middle aged subjects aged 40 to 65 years
- ProtocolRandomized, double-blind, placebo-controlled — the “gold standard” in studies
- ObjectiveInvestigate the efficacy of Mitopure on muscle function in otherwise healthy middle-aged, overweight and inactive individuals
Energy
We conducted a randomized placebo-controlled clinical trial with adults aged 61 and older. After 4 weeks, participants who received a daily dose of Mitopure (Urolithin A) had a significant improvement in mitochondrial signature, compared with participants in the placebo group.
Methodology
- Participants60 healthy elderly adults
- ProtocolRandomized, double-blind, placebo-controlled — the “gold standard” in studies
- ObjectiveDescribe the safety, bioavailability and beneficial impact of Urolithin A on key biomarkers of mitochondrial health
Bioavailability
Urolithin A is a compound derived from ellagitannin-rich foods like pomegranates, but not everyone’s microbiome can produce it. Supplementation offers a consistent way to access its benefits.
In a human clinical trial, a 500 mg dose of Mitopure (Urolithin A) delivered 6 times higher exposure compared to drinking 100% pomegranate juice.
Methodology
- Participants: 100 healthy adults, ages 18–80
- Protocol: Randomized, double-blind, placebo-controlled
- Objective: Assess how direct Urolithin A supplementation can overcome microbiome and dietary variability
Your cells feel the benefits before you do
“This is a supplement I use myself everyday to be as healthy as I can, for as long as I can.”
Functional Medicine Physician, 15x New York Times Bestselling Author
“No other supplement does what Timeline can. It is an amazing advance for muscle health and longevity.”
Founder Institute for Muscle-Centric Medicine®
“The latest clinical studies crystallize how Mitopure can be a real game-changer for human health.”
Scientific Advisor
“Mitochondrial decline is a key hallmark of aging and Mitopure is one of the most promising compounds in our field”
CEO Buck Institute for Research on Aging, Scientific Advisor
We love questions
Why should I take Mitopure Gummies?
Why should I take Mitopure Gummies?
Mitopure is a breakthrough supplement clinically proven to renew aging cells. A pure and patented form of the longevity nutrient Urolithin A, it works by converting cellular damage into energy, for improved muscle function, recovery and more.
Mitopure gummies are an easy, tasty way to get your daily dose of cellular rejuvenation.
How do I take the gummies?
How do I take the gummies?
Take 2 gummies daily for the foundational daily dose, or 4 gummies daily for 1000mg Mitopure. Gummies can be taken with meals or on an empty stomach. For optimal results, use consistently for at least four months and beyond.
I already take Mitopure. Can I take the gummies at the same time?
I already take Mitopure. Can I take the gummies at the same time?
Yes, you can combine gummies with another form of Mitopure (2 softgels or 1 stickpack of Berry Powder) as long as you do not exceed the maximum recommended dose of 1000mg/day.
Are these gummies vegan, gluten-free or allergen-friendly?
Are these gummies vegan, gluten-free or allergen-friendly?
Mitopure Gummies are vegan, gluten-free and sugar-free. They are made without milk, eggs, nuts, crustaceans, shellfish, wheat, soy and sesame.
Do these gummies contain any artificial ingredients or sweeteners?
Do these gummies contain any artificial ingredients or sweeteners?
Mitopure Gummies contain no artificial sweeteners, colors or flavors. They are sweetened with Reb M, which is a natural ingredient derived from stevia.